NOVARON Antibacterial Agent for Fibers and Films
Features
• Can be incorporated into fibers during spinning
• High heat resistance (800°C)
• Long-lasting antibacterial performance
Metal ions act on enzymes inside bacterial cells,
inhibiting their metabolic activity
Grade
| Grade | Characteristics | Average Particle Size (μm) | Specific Gravity | Moisture Content (wt%) |
|---|---|---|---|---|
| AG300 | General-purpose | 1 | 3.0 | 0.2 |
| AG1100 | High antibacterial activity | 1 | 3.0 | 0.2 |
| AGT330F | For fibers | 1 | 4.2 | 0.4 |
| VZF200S | Low discoloration | 2 | 3.6 | 0.5 |
1) Includes grades registered with the U.S. FDA and EPA
2) Includes products registered with SIAA (Society of International Sustaining Growth for Antibacterial Articles)
Fiber Processing Performance
The small particle size and narrow particle-size distribution enable compounding and melt spinning. Low moisture content and low hygroscopicity help prevent foaming during processing.
Antibacterial Performance
Minimum Inhibitory Concentration (MIC)
* Minimum concentration of antibacterial agent required to inhibit cell proliferation (μg/mL)
| Microorganism | Characteristics | AG300 |
|---|---|---|
| Escherichia coli | Indicator organism for food and drinking-water contamination | 125 |
| Escherichia coli O157:H7 | Vero toxin-producing bacterium that can cause food poisoning | 200 |
| Pseudomonas aeruginosa | Pathogen associated with spoilage of fish and meat | 125 |
| Salmonella | Bacterium that can cause typhoid fever and food poisoning | 250 |
| Staphylococcus aureus | Bacterium that can cause suppuration, sepsis, and food poisoning | 250 |
| Methicillin-resistant Staphylococcus aureus (MRSA) | Pathogen associated with healthcare-acquired infections | 250 |
| Bacillus subtilis | A major spoilage organism in milk and meat | 250 |
| Klebsiella pneumoniae | Bacterium that can cause pneumonia, urinary tract infections, and sepsis | 128 |
Antibacterial Performance in Polyester Fiber — Addition Rate: 0.5%
* Bacterial growth on the treated fabric is compared with that on the reference fabric and expressed as the difference in common logarithms.
• Initial performance is equivalent.
• After laundering, NOVARON retains its effectiveness, while other types of antibacterial agents show reduced performance.
Antibacterial Activity after Laundering
* Comparison with a conventional inorganic antibacterial agent (JIS L 1902)
Safety
| Test Item | Test Conditions | AG300 (Representative Grade) |
|---|---|---|
| Acute Oral Toxicity | OECD423 | >5000 mg/kg |
| Mutagenicity | OECD417 | Negative |
| Primary Skin Irritation | OECD404 | No irritation observed |
| Skin Sensitization | OECD406 | Negative |
| Cytotoxicity | Japanese Pharmacopoeia, 13th Edition | 69–88 μg/mL |